청각 뇌신경 영상 연구실 (AUDITORY NEUROIMAGING LABORATORY)

연구주제

  • 청각 생리 및 병리와 관련된 구조적-기능적 중추 신경계 영상 연구

PI 및 연구원 소개

  • 교  수 : 남의철
  • 연구원 : 태우석 박사, 나탈리아 야꾸니나 박사

연구실 소개

  • 기능적 자기공명 영상(functional MRI) , 확산텐서영상 (DTI, diffusion tensor imaging), 형태적 분석(Morphometric volumetry), EEG-MRI 등의 뇌 영상 연구기법 등을 이용하여 청각 중추의 기능을 평가하고 난청, 이명, 어지럼증과 관련된 중추 병리 기전을 규명하려는 연구들을 진행함.

연구 성과 소개

  • 대표 발표 논문

    • Activation of auditory white matter tracts as revealed by functional magnetic resonance imaging. Neuroradiology. 2014 Apr 16. [Epub ahead of print]
    • Progressive decrease of N-acetylaspartate to total creatine ratio in the pregenual anterior cingulate cortex in patients with major depressive disorder: longitudinal 1H-MR spectroscopy study. Acta Radiol. 2013 Sep 12;55(5):594-603. [Epub ahead of print]
    • Spatiotemporal Segregation of Neural Response to Auditory Stimulation: An fMRI Study Using Independent Component Analysis and Frequency-Domain Analysis. PLoS One. 2013 Jun 18;8(6):e66424.
    • Clonazepam quiets tinnitus: a randomised crossover study with Ginkgo biloba. J Neurol Neurosurg Psychiatry. 2012 Aug;83(8):821-7
    • Development of sound measurement systems for auditory functional magnetic resonance imaging. Magn Reson Imaging. 2008 Jun;26(5):715-20
    • Validation of hippocampal volumes measured using a manual method and two automated methods (FreeSurfer and IBASPM) in chronic major depressive disorder. Neuroradiology. 2008 Jul;50(7):569-81.
    • Electrocochleography is more sensitive than distortion-product otoacoustic emission test for detecting noise-induced temporary threshold shift. Otolaryngol Head Neck Surg. 2005 Oct;133(4):619-24.

  • 최근 학회발표

    • 014-6 The 20th Annual Meeting of the Organization for Human Brain Mapping (Germany) 포스터발표:
      1) Voxel based morphometry and shape analysis ofcorpus callosum in major depressive disorder
      2) Applicability of sparse temporal acquisitiontechnique in resting-state brain network analysis
      3) Effect of scanner noise on brain networks:an auditory stimulation fMRI study
    • 2014-4 제88차 대한이비인후과학회 학술대회 구연: Activation of auditory white matter tracts as revealed by functional magnetic resonance imaging
    • 2014-3 8th International TRI tinnitus Conference (New Zealand) 포스터 발표: Prevalence and Factors Associated with Neck and Jaw Muscle Modulation of Tinnitus
    • 2014-3 제48차 대한이과학회 학술대회 특강: Transcutaneous vagus nerve stimulation with notched music therapy
    • 2013-6 19th Annual Meeting of the Organization of Human Brain Mapping (Germany) 포스터 발표: Functional pathway of human central auditory system revealed by gray and white matter´s BOLD signal
    • 2013-6 IFOS 2013 – 20th International Federation of Oto-rhino-laryngological Societies World Congress (Seoul) 포스터발표: INCIDENCE AND ASSOCIATED FACTORS OF TINNITUSMODULATION BY NECK AND JAW
    • 2013 이과학 기초연구 세미나 특강: Optimized fMRI of cortical and subcortical auditory pathway
    • 2013 Asan Forum on Otology-Neurotology 특강: Emerging Tinnitus Treatments
    • 2012-6 Sixth International Conference on Tinnitus (Belgium) 구연: Clonazepam Quiets Tinnitus:a Randomized Crossover Study with Ginkgo Biloba
    • 2012-2 BIT´s 3rd Annual World Congress of NeuroTalk-2012 (China) Invited lecture: Functional Imaging on Tinnitus