기능적 자기공명 영상(functional MRI) , 확산텐서영상 (DTI, diffusion tensor imaging), 형태적 분석(Morphometric volumetry), EEG-MRI 등의 뇌 영상 연구기법 등을 이용하여 청각 중추의 기능을 평가하고 난청, 이명, 어지럼증과 관련된 중추 병리 기전을 규명하려는 연구들을 진행함.
연구 성과 소개
대표 발표 논문
Activation of auditory white matter tracts as revealed by functional magnetic resonance imaging. Neuroradiology. 2014 Apr 16. [Epub ahead of print]
Progressive decrease of N-acetylaspartate to total creatine ratio in the pregenual anterior cingulate cortex in patients with major depressive disorder: longitudinal 1H-MR spectroscopy study. Acta Radiol. 2013 Sep 12;55(5):594-603. [Epub ahead of print]
Spatiotemporal Segregation of Neural Response to Auditory Stimulation: An fMRI Study Using Independent Component Analysis and Frequency-Domain Analysis. PLoS One. 2013 Jun 18;8(6):e66424.
Clonazepam quiets tinnitus: a randomised crossover study with Ginkgo biloba. J Neurol Neurosurg Psychiatry. 2012 Aug;83(8):821-7
Development of sound measurement systems for auditory functional magnetic resonance imaging. Magn Reson Imaging. 2008 Jun;26(5):715-20
Validation of hippocampal volumes measured using a manual method and two automated methods (FreeSurfer and IBASPM) in chronic major depressive disorder. Neuroradiology. 2008 Jul;50(7):569-81.
Electrocochleography is more sensitive than distortion-product otoacoustic emission test for detecting noise-induced temporary threshold shift. Otolaryngol Head Neck Surg. 2005 Oct;133(4):619-24.
014-6 The 20th Annual Meeting of the Organization for Human Brain Mapping (Germany) 포스터발표:
1) Voxel based morphometry and shape analysis ofcorpus callosum in major depressive disorder
2) Applicability of sparse temporal acquisitiontechnique in resting-state brain network analysis
3) Effect of scanner noise on brain networks:an auditory stimulation fMRI study
2014-4 제88차 대한이비인후과학회 학술대회 구연: Activation of auditory white matter tracts as revealed by functional magnetic resonance imaging
2014-3 8th International TRI tinnitus Conference (New Zealand) 포스터 발표: Prevalence and Factors Associated with Neck and Jaw Muscle Modulation of Tinnitus
2014-3 제48차 대한이과학회 학술대회 특강: Transcutaneous vagus nerve stimulation with notched music therapy
2013-6 19th Annual Meeting of the Organization of Human Brain Mapping (Germany) 포스터 발표: Functional pathway of human central auditory system revealed by gray and white matter´s BOLD signal
2013-6 IFOS 2013 – 20th International Federation of Oto-rhino-laryngological Societies World Congress (Seoul) 포스터발표: INCIDENCE AND ASSOCIATED FACTORS OF TINNITUSMODULATION BY NECK AND JAW
2013 이과학 기초연구 세미나 특강: Optimized fMRI of cortical and subcortical auditory pathway
2013 Asan Forum on Otology-Neurotology 특강: Emerging Tinnitus Treatments
2012-6 Sixth International Conference on Tinnitus (Belgium) 구연: Clonazepam Quiets Tinnitus:a Randomized Crossover Study with Ginkgo Biloba
2012-2 BIT´s 3rd Annual World Congress of NeuroTalk-2012 (China) Invited lecture: Functional Imaging on Tinnitus